Ney, M.; Sirohi, P.; Shmidov, Y.; Singh, A.; Wadsworth, G.; Li, X.; Zheng, J.; Peng, E.; Fan, L.; Mahendran, T. S.; Deshpande, S.; Tripathi, N.; Su, J. C.; Milligan, J. J.; Wang, Y.-X.; Banerjee, P. R.; Chilkoti, A. Intrinsically Disordered Protein Coating for Oral Delivery of Peptide Drugs. Cell Biomaterials 2026, 100460. https://doi.org/10.1016/j.celbio.2026.100460.

Kim, Sarah Yeon-Kyoung, Taranpreet Kaur, Yulia Shmidov, Matthew Yiren Wang, Lixin Fan, Abigail Leo, Nicolas Angustia, Yan Xiang, Daniel Reker, and Ashutosh Chilkoti. “Genetically Encoded Sterol-Modification of a Synthetic Intrinsically Disordered Protein Drives Its Self-Assembly Into Diverse Morphologies.” Small (Weinheim an Der Bergstrasse, Germany) 22, no. 19 (April 2026): e09658. https://doi.org/10.1002/smll.202509658.

Sirohi, Parul, Brooke E. Silverstein, Yulia Shmidov, Sonal Deshpande, Joy Tong, Yvonne Y. Ma, Chinmay S. Potnis, et al. “All-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery.” Advanced Science (Weinheim, Baden-Wurttemberg, Germany) 13, no. 17 (March 2026): e17048. https://doi.org/10.1002/advs.202517048.

Milligan, Joshua J., Rachel L. Strader, Arunangshu Chakrabarty, Max Ney, Parul Sirohi, Jonathan C. Su, Anastasia K. Varanko, et al. “Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer.” Adv Sci (Weinh) 12, no. 37 (October 2025): e03591. https://doi.org/10.1002/advs.202503591.

Yvonne Y. Ma, Parul Sirohi, and Ashutosh Chilkoti. “Strategies for Improving Endosomal Escape of Polymeric Nanoparticles.” Bioconjugate Insights, 2025; 1(4), 109-134. https://doi.org/10.18609/bci.2025.023

Quintana, Adam, Linying Li, Ashutosh Chilkoti, Gabriel P. López, and Nick J. Carroll. “Rational Design of Thermoresponsive Elastin-Like Protein Monolayers for Nonenzymatic Cell Harvesting.” Biomacromolecules 26, no. 9 (September 2025): 5958–64. https://doi.org/10.1021/acs.biomac.5c00861.

Zheng, Chuanbao, Yulia Shmidov, Anastasia K. Varanko, Sonal Deshpande, Yunqi Yang, Daniel M. Shapiro, Zhisen Zhang, Han Zuilhof, Ashutosh Chilkoti, and Renko de Vries. “Nonfouling Coatings from Synthetic Intrinsically Disordered Proteins.” Small (Weinheim an Der Bergstrasse, Germany) 21, no. 34 (August 2025): e2504365. https://doi.org/10.1002/smll.202504365.

Su, J. C., G. M. Kelly, J. J. Milligan, S. Deshpande, R. L. Strader, M. R. Ney, N. Peterson, et al. “Spatiotemporal Control of IL-12 Delivery Improves Its Efficacy in Treatment of Solid Tumors.” Advanced Therapeutics 8, no. 8 (August 1, 2025). https://doi.org/10.1002/adtp.202500077.

Ata, Hirotaka, Madeleine E. Hull, William M. Geisler, Sixto M. Leal, and Ashutosh Chilkoti. “Rapid, Amplification-free, RNA-based Uropathogen Detection With LbuCas13a.” Open Forum Infectious Diseases 12, no. 8 (August 2025): ofaf477. https://doi.org/10.1093/ofid/ofaf477.

Mallory, Micah, Emma Grace Johnson, Soumen Saha, Sanika Pandit, Joshua T. McCune, Mengnan Dennis, Jessica M. Gluck, et al. “From saccharides to synthetics: exploring biomaterial scaffolds as cell transduction enhancers.” Biomaterials Science 13, no. 13 (June 2025): 3585–97. https://doi.org/10.1039/d4bm01588f.

Putman, Rachael, Neill Li, Daniel Y. Joh, Stefan Roberts, Tyler Pidgeon, Suhail Mithani, and Ashutosh Chilkoti. “Designing Next-Generation Biomaterials to Enhance Peripheral Nerve Repair and Reconstruction.” J Biomed Mater Res A 113, no. 6 (June 2025): e37930. https://doi.org/10.1002/jbm.a.37930.

Lee, Dongheon, Mackenzie T. Walls, Ka-Hei Siu, Yifan Dai, Ke Xu, Clifford P. Brangwynne, Ashutosh Chilkoti, José L. Avalos, and Lingchong You. “Principles of Metabolic Pathway Control by Biomolecular Condensates in Cells.” Nature Chemical Engineering 2, no. 3 (March 12, 2025): 198–208. https://doi.org/10.1038/s44286-025-00193-y.

Shapiro, Daniel Mark, Sonal Deshpande, Seyed Ali Eghtesadi, Miranda Zhong, Cassio Mendes Fontes, David Fiflis, Dahlia Rohm, et al. “Synthetic biomolecular condensates enhance translation from a target mRNA in living cells.” Nat Chem 17, no. 3 (March 2025): 448–56. https://doi.org/10.1038/s41557-024-01706-7.

Varanko, Anastasia K., Sonal Deshpande, Xinghai Li, and Ashutosh Chilkoti. “Binding Strength, Not Valency, Dictates Accumulation and Penetration of Affinity Targeted Macromolecules into Solid Tumors.” Biomacromolecules 26, no. 1 (January 2025): 503–13. https://doi.org/10.1021/acs.biomac.4c01303.

Varanko, Anastasia K., Sonal Deshpande, Xinghai Li, and Ashutosh Chilkoti. "Binding Strength, Not Valency, Dictates Accumulation and Penetration of Affinity Targeted Macromolecules into Solid Tumors." Biomacromolecules 26, no. 1 (2024), December 27, 2024. https://pubs.acs.org/doi/full/10.1021/acs.biomac.4c01303.

Saha, Soumen, Samagya Banskota, Parisa Yousefpour, Jeffrey L. Schaal, Nikita Zakharov, Jianqiao Liu, Michael Dzuricky, et al. “Preclinical Development of a Genetically Engineered Albumin-Binding Nanoparticle of Paclitaxel.” Small Science 4, no. 11 (November 2024): 2400153. https://doi.org/10.1002/smsc.202400153.

Lee, Dongheon, Yifan Dai, Hye-In Son, Kyeri Kim, Ashutosh Chilkoti, and Lingchong You. "Biomolecular Phase Separation Suppresses Gene Expression in Bacteria." In 2024 AIChE Annual Meeting. AIChE, 2024.

Dai, Yifan, Zhengqing Zhou, Wen Yu, Yuefeng Ma, Kyeri Kim, Nelson Rivera, Javid Mohammed, et al. “Biomolecular condensates regulate cellular electrochemical equilibria.” Cell 187, no. 21 (October 2024): 5951-5966.e18. https://doi.org/10.1016/j.cell.2024.08.018.

Stormo, Benjamin M., Grace A. McLaughlin, Ameya P. Jalihal, Logan K. Frederick, Sierra J. Cole, Ian Seim, Fred S. Dietrich, Ashutosh Chilkoti, and Amy S. Gladfelter. “Intrinsically disordered sequences can tune fungal growth and the cell cycle for specific temperatures.” Curr Biol 34, no. 16 (August 19, 2024): 3722-3734.e7. https://doi.org/10.1016/j.cub.2024.07.015.

Tang, Nicholas C., Jonathan C. Su, Yulia Shmidov, Garrett Kelly, Sonal Deshpande, Parul Sirohi, Nikhil Peterson, and Ashutosh Chilkoti. “Synthetic intrinsically disordered protein fusion tags that enhance protein solubility.” Nature Communications 15, no. 1 (May 2024): 3727. https://doi.org/10.1038/s41467-024-47519-7.

Li, Zongru, Qionghua Shen, Emery T. Usher, Andrew P. Anderson, Manuel Iburg, Richard Lin, Brandon Zimmer, et al. “Phase transition of GvpU regulates gas vesicle clustering in bacteria.” Nature Microbiology 9, no. 4 (April 2024): 1021–35. https://doi.org/10.1038/s41564-024-01648-3.

Walter, Vivien, Tatiana Schmatko, Pierre Muller, André P. Schroder, Sarah R. MacEwan, Ashutosh Chilkoti, and Carlos M. Marques. “Negative lipid membranes enhance the adsorption of TAT-decorated elastin-like polypeptide micelles.” Biophysical Journal 123, no. 7 (April 2024): 901–8. https://doi.org/10.1016/j.bpj.2024.03.001.

Albarghouthi, Faris M., Daria Semeniak, Iman Khanani, James L. Doherty, Brittany N. Smith, Matthew Salfity, Quentin MacFarlane, et al. “Addressing Signal Drift and Screening for Detection of Biomarkers with Carbon Nanotube Transistors.” ACS Nano, February 2024. https://doi.org/10.1021/acsnano.3c11679.

Strader, Rachel L., Yulia Shmidov, and Ashutosh Chilkoti. “Encoding Structure in Intrinsically Disordered Protein Biomaterials.” Accounts of Chemical Research 57, no. 3 (February 2024): 302–11. https://doi.org/10.1021/acs.accounts.3c00624.

Deshpande, Sonal, Yunqi Yang, Stefan Zauscher, and Ashutosh Chilkoti. “Enzymatic Synthesis of Aptamer-Polynucleotide Nanoparticles with High Anticancer Drug Loading for Targeted Delivery.” Biomacromolecules 25, no. 1 (January 2024): 155–64. https://doi.org/10.1021/acs.biomac.3c00888.

Deshpande, Sonal, Yunqi Yang, Stefan Zauscher, and Ashutosh Chilkoti. “Enzymatic Synthesis of Aptamer-Polynucleotide Nanoparticles with High Anticancer Drug Loading for Targeted Delivery.” Biomacromolecules 25, no. 1 (January 2024): 155–64. https://doi.org/10.1021/acs.biomac.3c00888.

Sethi, Vaishali, Dana Cohen-Gerassi, Sagi Meir, Max Ney, Yulia Shmidov, Gil Koren, Lihi Adler-Abramovich, Ashutosh Chilkoti, and Roy Beck. “Modulating hierarchical self-assembly in thermoresponsive intrinsically disordered proteins through high-temperature incubation time.” Scientific Reports 13, no. 1 (December 2023): 21688. https://doi.org/10.1038/s41598-023-48483-w.

Lazar, K. M., S. Shetty, A. Chilkoti, and J. H. Collier. “Immune-active polymeric materials for the treatment of inflammatory diseases.” Current Opinion in Colloid and Interface Science 67 (October 1, 2023). https://doi.org/10.1016/j.cocis.2023.101726.

Semeniak, Daria, Daniela F. Cruz, Ashutosh Chilkoti, and Maiken H. Mikkelsen. “Plasmonic Fluorescence Enhancement in Diagnostics for Clinical Tests at Point-of-Care: A Review of Recent Technologies.” Advanced Materials (Deerfield Beach, Fla.) 35, no. 34 (August 2023): e2107986. https://doi.org/10.1002/adma.202107986.

Vahabi, Hamed, Jason Liu, Yifan Dai, Daniel Y. Joh, Rhett Britton, Jacob Heggestad, David Kinnamon, Satyam Rajput, and Ashutosh Chilkoti. “A gravity-driven droplet fluidic point-of-care test.” Device 1, no. 1 (July 2023): 100009. https://doi.org/10.1016/j.device.2023.100009.

Kinnamon, David S., Jacob T. Heggestad, Jason Liu, Thu Nguyen, Vo Ly, Angus M. Hucknall, Cassio M. Fontes, et al. “Environmentally Resilient Microfluidic Point-of-Care Immunoassay Enables Rapid Diagnosis of Talaromycosis.” ACS Sens 8, no. 6 (June 23, 2023): 2228–36. https://doi.org/10.1021/acssensors.3c00209.

Dai, Yifan, Christian F. Chamberlayne, Marco S. Messina, Christopher J. Chang, Richard N. Zare, Lingchong You, and Ashutosh Chilkoti. “Interface of biomolecular condensates modulates redox reactions.” Chem 9, no. 6 (June 2023): 1594–1609. https://doi.org/10.1016/j.chempr.2023.04.001.

Burrow, Damon T., Jacob T. Heggestad, David S. Kinnamon, and Ashutosh Chilkoti. “Engineering Innovative Interfaces for Point-of-Care Diagnostics.” Current Opinion in Colloid & Interface Science, June 2023, 101718. https://doi.org/10.1016/j.cocis.2023.101718.

Heggestad, Jacob T., Rhett J. Britton, David S. Kinnamon, Jason Liu, Jack G. Anderson, Daniel Y. Joh, Zachary Quinn, et al. “COVID-19 Diagnosis and SARS-CoV-2 Strain Identification by a Rapid, Multiplexed, Point-of-Care Antibody Microarray.” Anal Chem 95, no. 13 (April 4, 2023): 5610–17. https://doi.org/10.1021/acs.analchem.2c05180.

Y. Dai, You, L. , and Chilkoti, A. , “Engineering synthetic biomolecular condensates”, Nature Reviews Bioengineering, 2023.

Dai, Yifan, Mina Farag, Dongheon Lee, Xiangze Zeng, Kyeri Kim, Hye-In Son, Xiao Guo, et al. “Programmable synthetic biomolecular condensates for cellular control.” Nature Chemical Biology 19, no. 4 (April 2023): 518–28. https://doi.org/10.1038/s41589-022-01252-8.

Dai, Yifan, Lingchong You, and Ashutosh Chilkoti. “Engineering synthetic biomolecular condensates.” Nature Reviews Bioengineering, April 2023, 1–15. https://doi.org/10.1038/s44222-023-00052-6.

Ozer, Imran, Anna Slezak, Parul Sirohi, Xinghai Li, Nikita Zakharov, Yunxin Yao, Jeffrey I. Everitt, et al. “An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug.” Biomaterials 294 (March 2023): 121985. https://doi.org/10.1016/j.biomaterials.2022.121985.

Olson, Lyra B., Nicole I. Hunter, Rachel E. Rempel, Haixiang Yu, Diane M. Spencer, Cynthia Z. Sullenger, William S. Greene, et al. “Mixed-surface polyamidoamine polymer variants retain nucleic acid-scavenger ability with reduced toxicity.” IScience 25, no. 12 (December 22, 2022): 105542. https://doi.org/10.1016/j.isci.2022.105542.

J. Haley, Jones, J. B. , Petraki, S. , Callander, M. , Shrestha, S. , Springfield, E. , Adamson, L. , Chilkoti, A. , Dzuricky, M. J. , and Luginbuhl, K. M. , “IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing”, Cell & Gene Therapy Insights, vol. 8, no. 10, pp. 1287-1300, 2022.

Schaal, Jeffrey L., Jayanta Bhattacharyya, Jeremy Brownstein, Kyle C. Strickland, Garrett Kelly, Soumen Saha, Joshua Milligan, et al. “Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours.” Nat Biomed Eng 6, no. 10 (October 2022): 1148–66. https://doi.org/10.1038/s41551-022-00949-4.

Roden, Christine A., Yifan Dai, Catherine A. Giannetti, Ian Seim, Myungwoon Lee, Rachel Sealfon, Grace A. McLaughlin, et al. “Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.” Nucleic Acids Res 50, no. 14 (August 12, 2022): 8168–92. https://doi.org/10.1093/nar/gkac596.

Saha, Soumen, Samagya Banskota, Jianqiao Liu, Nikita Zakharov, Michael Dzuricky, Xinghai Li, Ping Fan, et al. “Genetically Engineered Nanoparticles of Asymmetric Triblock Polypeptide with a Platinum(IV) Cargo Outperforms a Platinum(II) Analog and Free Drug in a Murine Cancer Model.” Nano Lett 22, no. 14 (July 27, 2022): 5898–5908. https://doi.org/10.1021/acs.nanolett.2c01850.

Lin, Kevin H., Justine C. Rutter, Abigail Xie, Shane T. Killarney, Camille Vaganay, Chaima Benaksas, Frank Ling, et al. “P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.” Nat Cancer 3, no. 7 (July 2022): 837–51. https://doi.org/10.1038/s43018-022-00394-x.

Kinnamon, David S., Jacob T. Heggestad, Jason Liu, and Ashutosh Chilkoti. “Technologies for Frugal and Sensitive Point-of-Care Immunoassays.” Annual Review of Analytical Chemistry (Palo Alto, Calif.) 15, no. 1 (June 2022): 123–49. https://doi.org/10.1146/annurev-anchem-061020-123817.

Ozer, Imran, Garrett Kelly, Renpeng Gu, Xinghai Li, Nikita Zakharov, Parul Sirohi, Smita K. Nair, et al. “Polyethylene Glycol-Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart.” Adv Sci (Weinh) 9, no. 11 (April 2022): e2103672. https://doi.org/10.1002/advs.202103672.

Milligan, Joshua J., Soumen Saha, Irene C. Jenkins, and Ashutosh Chilkoti. “Genetically encoded elastin-like polypeptide nanoparticles for drug delivery.” Current Opinion in Biotechnology 74 (April 2022): 146–53. https://doi.org/10.1016/j.copbio.2021.11.006.

Kelly, Garrett, Joshua J. Milligan, Eric M. Mastria, Sarah Kim, Stephanie R. Zelenetz, Jarrett Dobbins, Leon Y. Cai, Xinghai Li, Smita K. Nair, and Ashutosh Chilkoti. “Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot.” J Control Release 343 (March 2022): 267–76. https://doi.org/10.1016/j.jconrel.2022.01.024.

Ozer, Imran, George A. Pitoc, Juliana M. Layzer, Angelo Moreno, Lyra B. Olson, Kyle D. Layzer, Angus M. Hucknall, Bruce A. Sullenger, and Ashutosh Chilkoti. “PEG-Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response.” Adv Mater 34, no. 10 (March 2022): e2107852. https://doi.org/10.1002/adma.202107852.

Heggestad, Jacob T., David S. Kinnamon, Jason Liu, Daniel Y. Joh, Cassio M. Fontes, Qingshan Wei, Aydogan Ozcan, Angus M. Hucknall, and Ashutosh Chilkoti. “Smartphone Enabled Point-of-Care Detection of Serum Biomarkers.” Methods in Molecular Biology (Clifton, N.J.) 2393 (January 2022): 343–65. https://doi.org/10.1007/978-1-0716-1803-5_19.

Heggestad, Jacob T., Rhett J. Britton, David S. Kinnamon, Simone A. Wall, Daniel Y. Joh, Angus M. Hucknall, Lyra B. Olson, et al. “Rapid test to assess the escape of SARS-CoV-2 variants of concern.” Sci Adv 7, no. 49 (December 3, 2021): eabl7682. https://doi.org/10.1126/sciadv.abl7682.

J. T. Heggestad, Kinnamon, D. S. , Liu, J. , Joh, D. Y. , Fontes, C. M. , Wei, Q. , Ozcan, A. , Hucknall, A. M. , and Chilkoti, A. , Methods in Molecular BiologyBiomedical Engineering TechnologiesSmartphone Enabled Point-of-Care Detection of Serum Biomarkers, vol. 2393. New York, NY: Springer US, 2021, pp. 343 - 365.

Weber, Patrick, Michael Dzuricky, Junseon Min, Irene Jenkins, and Ashutosh Chilkoti. “Concentration-Independent Multivalent Targeting of Cancer Cells by Genetically Encoded Core-Crosslinked Elastin/Resilin-like Polypeptide Micelles.” Biomacromolecules 22, no. 10 (October 2021): 4347–56. https://doi.org/10.1021/acs.biomac.1c00897.

Joh, Daniel Y., Jacob T. Heggestad, Shengwei Zhang, Gray R. Anderson, Jayanta Bhattacharyya, Suzanne E. Wardell, Simone A. Wall, et al. “Author Correction: Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates.” NPJ Breast Cancer 7, no. 1 (September 17, 2021): 126. https://doi.org/10.1038/s41523-021-00335-4.

Navarro, Luis A., Justin J. Ryan, Michael Dzuricky, Michael Gradzielski, Ashutosh Chilkoti, and Stefan Zauscher. “Microphase Separation of Resilin-like and Elastin-like Diblock Copolypeptides in Concentrated Solutions.” Biomacromolecules 22, no. 9 (September 2021): 3827–38. https://doi.org/10.1021/acs.biomac.1c00672.

Joh, Daniel Y., Jacob T. Heggestad, Shengwei Zhang, Gray R. Anderson, Jayanta Bhattacharyya, Suzanne E. Wardell, Simone A. Wall, et al. “Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates.” NPJ Breast Cancer 7, no. 1 (July 2, 2021): 85. https://doi.org/10.1038/s41523-021-00290-0.

Jenkins, Irene C., Joshua J. Milligan, and Ashutosh Chilkoti. “Genetically Encoded Elastin-Like Polypeptides for Drug Delivery.” Advanced Healthcare Materials 10, no. 13 (July 2021): e2100209. https://doi.org/10.1002/adhm.202100209.

Shapiro, Daniel Mark, Max Ney, Seyed Ali Eghtesadi, and Ashutosh Chilkoti. “Protein Phase Separation Arising from Intrinsic Disorder: First-Principles to Bespoke Applications.” The Journal of Physical Chemistry. B 125, no. 25 (July 2021): 6740–59. https://doi.org/10.1021/acs.jpcb.1c01146.

Heggestad, Jacob T., David S. Kinnamon, Lyra B. Olson, Jason Liu, Garrett Kelly, Simone A. Wall, Solomon Oshabaheebwa, et al. “Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test.” Sci Adv 7, no. 26 (June 2021). https://doi.org/10.1126/sciadv.abg4901.

Fontes, Cassio M., Barbara D. Lipes, Jason Liu, Krystle N. Agans, Aiwei Yan, Patricia Shi, Daniela F. Cruz, et al. “Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR.” Sci Transl Med 13, no. 588 (April 7, 2021). https://doi.org/10.1126/scitranslmed.abd9696.

Hainline, Kelly M., Lucas S. Shores, Nicole L. Votaw, Zachary J. Bernstein, Sean H. Kelly, Chelsea N. Fries, Marisha S. Madhira, Caslin A. Gilroy, Ashutosh Chilkoti, and Joel H. Collier. “Modular complement assemblies for mitigating inflammatory conditions.” Proceedings of the National Academy of Sciences of the United States of America 118, no. 15 (April 2021): e2018627118. https://doi.org/10.1073/pnas.2018627118.

Laaß, Katharina, Felipe García Quiroz, Johannes Hunold, Stefan Roberts, Ashutosh Chilkoti, and Dariush Hinderberger. “Nanoscopic Dynamics Dictate the Phase Separation Behavior of Intrinsically Disordered Proteins.” Biomacromolecules 22, no. 2 (February 2021): 1015–25. https://doi.org/10.1021/acs.biomac.0c01768.

Zeng, Xiangze, Chengwen Liu, Martin J. Fossat, Pengyu Ren, Ashutosh Chilkoti, and Rohit V. Pappu. “Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures.” APL Materials 9, no. 2 (February 2021): 021119. https://doi.org/10.1063/5.0037438.

Li, Linying, C Wyatt Shields, Jin Huang, Yiqun Zhang, Korine A. Ohiri, Benjamin B. Yellen, Ashutosh Chilkoti, and Gabriel P. López. “Rapid capture of biomolecules from blood via stimuli-responsive elastomeric particles for acoustofluidic separation.” The Analyst 145, no. 24 (January 2021): 8087–96. https://doi.org/10.1039/d0an01164a.

Heggestad, Jacob T., Cassio M. Fontes, Daniel Y. Joh, Angus M. Hucknall, and Ashutosh Chilkoti. “In Pursuit of Zero 2.0: Recent Developments in Nonfouling Polymer Brushes for Immunoassays.” Advanced Materials (Deerfield Beach, Fla.) 32, no. 2 (January 2020): e1903285. https://doi.org/10.1002/adma.201903285.

Wang, Jing, Junseon Min, Seyed Ali Eghtesadi, Ravi S. Kane, and Ashutosh Chilkoti. “Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density.” ACS Nano 14, no. 1 (January 2020): 372–83. https://doi.org/10.1021/acsnano.9b05689.

Lee, J. S., R. T. Hill, A. Chilkoti, and W. L. Murphy. “Surface Patterning.” In Biomaterials Science an Introduction to Materials in Medicine, 553–73, 2020. https://doi.org/10.1016/B978-0-12-816137-1.00037-4.

Varanko, Anastasia, Soumen Saha, and Ashutosh Chilkoti. “Recent trends in protein and peptide-based biomaterials for advanced drug delivery.” Advanced Drug Delivery Reviews 156 (January 2020): 133–87. https://doi.org/10.1016/j.addr.2020.08.008.

Wang, Jing, Soumen Saha, Jeffrey L. Schaal, Parisa Yousefpour, Xinghai Li, and Ashutosh Chilkoti. “Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles.” Nano Letters 19, no. 11 (November 2019): 7977–87. https://doi.org/10.1021/acs.nanolett.9b03141.

Garcia Quiroz, Felipe, Nan K. Li, Stefan Roberts, Patrick Weber, Michael Dzuricky, Isaac Weitzhandler, Yaroslava G. Yingling, and Ashutosh Chilkoti. “Intrinsically disordered proteins access a range of hysteretic phase separation behaviors.” Science Advances 5, no. 10 (October 2019): eaax5177. https://doi.org/10.1126/sciadv.aax5177.

Dai, Zhuojun, Anna J. Lee, Stefan Roberts, Tatyana A. Sysoeva, Shuqiang Huang, Michael Dzuricky, Xiaoyu Yang, et al. “Versatile biomanufacturing through stimulus-responsive cell-material feedback.” Nature Chemical Biology 15, no. 10 (October 2019): 1017–24. https://doi.org/10.1038/s41589-019-0357-8.

Willems, Lione, Larissa van Westerveld, Stefan Roberts, Isaac Weitzhandler, Carlos Calcines Cruz, Armando Hernandez-Garcia, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide.” Biomacromolecules 20, no. 10 (October 2019): 3641–47. https://doi.org/10.1021/acs.biomac.9b00512.

Manzari, Mandana T., Gray R. Anderson, Kevin H. Lin, Ryan S. Soderquist, Merve Çakir, Mitchell Zhang, Chandler E. Moore, et al. “Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.” Sci Adv 5, no. 9 (September 2019): eaaw9162. https://doi.org/10.1126/sciadv.aaw9162.

Dzuricky, Michael, Sinan Xiong, Patrick Weber, and Ashutosh Chilkoti. “Avidity and Cell Uptake of Integrin-Targeting Polypeptide Micelles is Strongly Shape-Dependent.” Nano Letters 19, no. 9 (September 2019): 6124–32. https://doi.org/10.1021/acs.nanolett.9b02095.

Simon, Joseph R., Seyed Ali Eghtesadi, Michael Dzuricky, Lingchong You, and Ashutosh Chilkoti. “Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells.” Molecular Cell 75, no. 1 (July 2019): 66-75.e5. https://doi.org/10.1016/j.molcel.2019.05.010.

Varanko, Anastasia K., and Ashutosh Chilkoti. “Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes.” Advanced Healthcare Materials 8, no. 12 (June 2019): e1801509. https://doi.org/10.1002/adhm.201801509.

Willems, Lione, Stefan Roberts, Isaac Weitzhandler, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Inducible Fibril Formation of Silk-Elastin Diblocks.” ACS Omega 4, no. 5 (May 2019): 9135–43. https://doi.org/10.1021/acsomega.9b01025.

Joh, Daniel Y., Zackary Zimmers, Manav Avlani, Jacob T. Heggestad, Hakan B. Aydin, Nancy Ganson, Shourya Kumar, et al. “Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties.” Adv Healthc Mater 8, no. 8 (April 2019): e1801177. https://doi.org/10.1002/adhm.201801177.

Koc, Julian, Tomer Simovich, Eric Schönemann, Ashutosh Chilkoti, Harrison Gardner, Geoffrey W. Swain, Kelli Hunsucker, André Laschewsky, and Axel Rosenhahn. “Sediment challenge to promising ultra-low fouling hydrophilic surfaces in the marine environment.” Biofouling 35, no. 4 (April 2019): 454–62. https://doi.org/10.1080/08927014.2019.1611790.

Yousefpour, Parisa, Lucie Ahn, Joel Tewksbury, Soumen Saha, Simone A. Costa, Joseph J. Bellucci, Xinghai Li, and Ashutosh Chilkoti. “Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.” Small (Weinheim an Der Bergstrasse, Germany) 15, no. 12 (March 2019): e1804452. https://doi.org/10.1002/smll.201804452.

Banskota, Samagya, Parisa Yousefpour, Nadia Kirmani, Xinghai Li, and Ashutosh Chilkoti. “Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery.” Biomaterials 192 (February 2019): 475–85. https://doi.org/10.1016/j.biomaterials.2018.11.012.

Fontes, Cassio M., Rohan K. Achar, Daniel Y. Joh, Imran Ozer, Somnath Bhattacharjee, Angus Hucknall, and Ashutosh Chilkoti. “Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays.” Langmuir : The ACS Journal of Surfaces and Colloids 35, no. 5 (February 2019): 1379–90. https://doi.org/10.1021/acs.langmuir.8b01597.

Deshpande, Sonal, Yunqi Yang, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic synthesis and modification of high molecular weight DNA using terminal deoxynucleotidyl transferase.,” 627:163–88, 2019. https://doi.org/10.1016/bs.mie.2019.07.044.

Costa, Simone A., Davoud Mozhdehi, Michael J. Dzuricky, Farren J. Isaacs, Eric M. Brustad, and Ashutosh Chilkoti. “Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.” Nano Letters 19, no. 1 (January 2019): 247–54. https://doi.org/10.1021/acs.nanolett.8b03837.

Mozhdehi, Davoud, Kelli M. Luginbuhl, Michael Dzuricky, Simone A. Costa, Sinan Xiong, Fred C. Huang, Mae M. Lewis, Stephanie R. Zelenetz, Christian D. Colby, and Ashutosh Chilkoti. “Genetically Encoded Cholesterol-Modified Polypeptides.” Journal of the American Chemical Society 141, no. 2 (January 2019): 945–51. https://doi.org/10.1021/jacs.8b10687.

Roberts, Stefan, Tyler S. Harmon, Jeffrey L. Schaal, Vincent Miao, Kan Jonathan Li, Andrew Hunt, Yi Wen, et al. “Author Correction: Injectable tissue integrating networks from recombinant polypeptides with tunable order.” Nat Mater 17, no. 12 (December 2018): 1164. https://doi.org/10.1038/s41563-018-0233-z.

Roberts, Stefan, Tyler S. Harmon, Jeffrey L. Schaal, Vincent Miao, Kan Jonathan Li, Andrew Hunt, Yi Wen, et al. “Injectable tissue integrating networks from recombinant polypeptides with tunable order.” Nat Mater 17, no. 12 (December 2018): 1154–63. https://doi.org/10.1038/s41563-018-0182-6.

Yousefpour, Parisa, Jonathan R. McDaniel, Varun Prasad, Lucie Ahn, Xinghai Li, Rishi Subrahmanyan, Isaac Weitzhandler, Steven Suter, and Ashutosh Chilkoti. “Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy.” Nano Letters 18, no. 12 (December 2018): 7784–93. https://doi.org/10.1021/acs.nanolett.8b03558.

Ruff, Kiersten M., Stefan Roberts, Ashutosh Chilkoti, and Rohit V. Pappu. “Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers.” Journal of Molecular Biology 430, no. 23 (November 2018): 4619–35. https://doi.org/10.1016/j.jmb.2018.06.031.

Gu, Renpeng, Thomas Oweida, Yaroslava G. Yingling, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation.” Biomacromolecules 19, no. 8 (August 2018): 3525–35. https://doi.org/10.1021/acs.biomac.8b00816.

Li, Nan K., Stefan Roberts, Felipe Garcia Quiroz, Ashutosh Chilkoti, and Yaroslava G. Yingling. “Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides.” Biomacromolecules 19, no. 7 (July 2018): 2496–2505. https://doi.org/10.1021/acs.biomac.8b00099.

Mozhdehi, Davoud, Kelli M. Luginbuhl, Joseph R. Simon, Michael Dzuricky, Rüdiger Berger, H Samet Varol, Fred C. Huang, et al. “Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly.” Nature Chemistry 10, no. 5 (May 2018): 496–505. https://doi.org/10.1038/s41557-018-0005-z.

Dzuricky, Michael, Stefan Roberts, and Ashutosh Chilkoti. “Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins.” Biochemistry 57, no. 17 (May 2018): 2405–14. https://doi.org/10.1021/acs.biochem.8b00056.

Gilroy, Caslin A., Stefan Roberts, and Ashutosh Chilkoti. “Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action.” Journal of Controlled Release : Official Journal of the Controlled Release Society 277 (May 2018): 154–64. https://doi.org/10.1016/j.jconrel.2018.03.015.

Li, Linying, Nan K. Li, Qing Tu, Owen Im, Chia-Kuei Mo, Wei Han, William H. Fuss, et al. “Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers.” Biomacromolecules 19, no. 2 (February 2018): 298–306. https://doi.org/10.1021/acs.biomac.7b01307.

Costa, Simone A., Joseph R. Simon, Miriam Amiram, Lei Tang, Stefan Zauscher, Eric M. Brustad, Farren J. Isaacs, and Ashutosh Chilkoti. “Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides.” Advanced Materials (Deerfield Beach, Fla.) 30, no. 5 (February 2018). https://doi.org/10.1002/adma.201704878.

Mastria, Eric M., Leon Y. Cai, Matthew J. Kan, Xinghai Li, Jeffrey L. Schaal, Steven Fiering, Michael D. Gunn, Mark W. Dewhirst, Smita K. Nair, and Ashutosh Chilkoti. “Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity.” J Control Release 269 (January 10, 2018): 364–73. https://doi.org/10.1016/j.jconrel.2017.11.021.

Luginbuhl, Kelli M., Davoud Mozhdehi, Michael Dzuricky, Parisa Yousefpour, Fred C. Huang, Nicholas R. Mayne, Kristen L. Buehne, and Ashutosh Chilkoti. “Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs.” Angewandte Chemie (International Ed. in English) 56, no. 45 (November 2017): 13979–84. https://doi.org/10.1002/anie.201704625.

Wang, Jing, Michael Dzuricky, and Ashutosh Chilkoti. “The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles.” Nano Letters 17, no. 10 (October 2017): 5995–6005. https://doi.org/10.1021/acs.nanolett.7b02225.

“Correction for Joh et al., Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood.” Proc Natl Acad Sci U S A 114, no. 39 (September 26, 2017): E8315. https://doi.org/10.1073/pnas.1715292114.

Bhattacharyya, Jayanta, Xiu-Rong Ren, Robert A. Mook, Jiangbo Wang, Ivan Spasojevic, Richard T. Premont, Xinghai Li, Ashutosh Chilkoti, and Wei Chen. “Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.” Nanoscale 9, no. 34 (August 31, 2017): 12709–17. https://doi.org/10.1039/c7nr01973d.

Wang, Jing, Jayanta Bhattacharyya, Eric Mastria, and Ashutosh Chilkoti. “A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles.” J Control Release 260 (August 28, 2017): 100–110. https://doi.org/10.1016/j.jconrel.2017.05.032.

Joh, Daniel Y., Angus M. Hucknall, Qingshan Wei, Kelly A. Mason, Margaret L. Lund, Cassio M. Fontes, Ryan T. Hill, et al. “Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood.” Proc Natl Acad Sci U S A 114, no. 34 (August 22, 2017): E7054–62. https://doi.org/10.1073/pnas.1703200114.

Weitzhandler, Isaac, Michael Dzuricky, Ingo Hoffmann, Felipe Garcia Quiroz, Michael Gradzielski, and Ashutosh Chilkoti. “Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides.” Biomacromolecules 18, no. 8 (August 2017): 2419–26. https://doi.org/10.1021/acs.biomac.7b00589.

Tang, Lei, Luis A. Navarro, Ashutosh Chilkoti, and Stefan Zauscher. “High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation.” Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6778–82. https://doi.org/10.1002/anie.201700991.

MacEwan, Sarah R., and Ashutosh Chilkoti. “From Composition to Cure: A Systems Engineering Approach to Anticancer Drug Carriers.” Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6712–33. https://doi.org/10.1002/anie.201610819.

Han, Wei, Ashutosh Chilkoti, and Gabriel P. López. “Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release.” Nanoscale 9, no. 18 (May 2017): 6178–86. https://doi.org/10.1039/c7nr00172j.

Bhattacharyya, Jayanta, Isaac Weitzhandler, Shihan Bryan Ho, Jonathan R. McDaniel, Xinghai Li, Lei Tang, Jinyao Liu, Mark Dewhirst, and Ashutosh Chilkoti. “Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy.” Adv Funct Mater 27, no. 12 (March 24, 2017). https://doi.org/10.1002/adfm.201605421.

Weinberger, A., V. Walter, S. R. MacEwan, T. Schmatko, P. Muller, A. P. Schroder, A. Chilkoti, and C. M. Marques. “Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes.” Scientific Reports 7 (March 6, 2017). https://doi.org/10.1038/srep43963.

Ozer, Imran, and Ashutosh Chilkoti. “Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins.” Bioconjugate Chemistry 28, no. 3 (March 2017): 713–23. https://doi.org/10.1021/acs.bioconjchem.6b00652.

Widder, Katharina, Sarah R. MacEwan, Elisabeth Garanger, Vanesa Núñez, Sébastien Lecommandoux, Ashutosh Chilkoti, and Dariush Hinderberger. “Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers.” Soft Matter 13, no. 9 (March 2017): 1816–22. https://doi.org/10.1039/c6sm02427k.

Joh, Daniel Y., Felicia McGuire, Roozbeh Abedini-Nassab, Joseph B. Andrews, Rohan K. Achar, Zackary Zimmers, Darush Mozhdehi, et al. “Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments.” ACS Applied Materials & Interfaces 9, no. 6 (February 2017): 5522–29. https://doi.org/10.1021/acsami.6b15836.

Wang, Jing, Sarah R. MacEwan, and Ashutosh Chilkoti. “Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH.” Nano Letters 17, no. 2 (February 2017): 1226–32. https://doi.org/10.1021/acs.nanolett.6b05041.

MacEwan, Sarah R., Isaac Weitzhandler, Ingo Hoffmann, Jan Genzer, Michael Gradzielski, and Ashutosh Chilkoti. “Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides.” Biomacromolecules 18, no. 2 (February 2017): 599–609. https://doi.org/10.1021/acs.biomac.6b01759.

Luginbuhl, Kelli M., Jeffrey L. Schaal, Bret Umstead, Eric M. Mastria, Xinghai Li, Samagya Banskota, Susan Arnold, Mark Feinglos, David D’Alessio, and Ashutosh Chilkoti. “One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer.” Nat Biomed Eng 1 (2017). https://doi.org/10.1038/s41551-017-0078.

Gonzalez, Mark A., Joseph R. Simon, Ali Ghoorchian, Zachary Scholl, Shaoting Lin, Michael Rubinstein, Piotr Marszalek, Ashutosh Chilkoti, Gabriel P. López, and Xuanhe Zhao. “Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins.” Advanced Materials, 2017. https://doi.org/10.1002/adma.201604743.

Roberts, S., S. Costa, J. Schaal, J. R. Simon, M. Dzuricky, F. G. Quiroz, and A. Chilkoti. “2.5 Elastin-like polypeptides.” In Comprehensive Biomaterials II, 90–108, 2017. https://doi.org/10.1016/B978-0-12-803581-8.09308-5.

Banskota, Samagya, Parisa Yousefpour, and Ashutosh Chilkoti. “Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds.” Macromolecular Bioscience 17, no. 1 (January 2017). https://doi.org/10.1002/mabi.201600361.

Simon, Joseph R., Nick J. Carroll, Michael Rubinstein, Ashutosh Chilkoti, and Gabriel P. López. “Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity.” Nature Chemistry, 2017. https://doi.org/10.1038/nchem.2715.

Kwok, Kevin W. H., Wu Dong, Stella M. Marinakos, Jie Liu, Ashutosh Chilkoti, Mark R. Wiesner, Melissa Chernick, and David E. Hinton. “Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation.” Nanotoxicology 10, no. 9 (November 2016): 1306–17. https://doi.org/10.1080/17435390.2016.1206150.

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Faris Albarghouthi, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic transistors in a tri-axial magnetic field.” Lab Chip 16, no. 21 (October 18, 2016): 4181–88. https://doi.org/10.1039/c6lc00878j.

Gilroy, Caslin A., Kelli M. Luginbuhl, and Ashutosh Chilkoti. “Controlled release of biologics for the treatment of type 2 diabetes.” Journal of Controlled Release : Official Journal of the Controlled Release Society 240 (October 2016): 151–64. https://doi.org/10.1016/j.jconrel.2015.12.002.

Pham, An T., Ryohei Seto, Johannes Schönke, Daniel Y. Joh, Ashutosh Chilkoti, Eliot Fried, and Benjamin B. Yellen. “Crystallization kinetics of binary colloidal monolayers.” Soft Matter 12, no. 37 (October 2016): 7735–46. https://doi.org/10.1039/c6sm01072e.

Pang, Yan, Jinyao Liu, Yizhi Qi, Xinghai Li, and Ashutosh Chilkoti. “A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.” Angewandte Chemie (International Ed. in English) 55, no. 35 (August 2016): 10296–300. https://doi.org/10.1002/anie.201604661.

Liu, Jinyao, Yan Pang, Jayanta Bhattacharyya, Wenge Liu, Isaac Weitzhandler, Xinghai Li, and Ashutosh Chilkoti. “Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug.” Advanced Healthcare Materials 5, no. 15 (August 2016): 1868–73. https://doi.org/10.1002/adhm.201600230.

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa Van Heest, Cody Baker, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic Conductors and Diodes in a 3D Magnetic Field.” Adv Funct Mater 26, no. 22 (June 14, 2016): 4026–34. https://doi.org/10.1002/adfm.201503898.

Li, Linying, Chia-Kuei Mo, Ashutosh Chilkoti, Gabriel P. Lopez, and Nick J. Carroll. “Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides.” Biointerphases 11, no. 2 (June 2016): 021009. https://doi.org/10.1116/1.4952452.

Schaal, Jeffrey L., Xinghai Li, Eric Mastria, Jayanta Bhattacharyya, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.” J Control Release 228 (April 28, 2016): 58–66. https://doi.org/10.1016/j.jconrel.2016.02.040.

Tang, Nicholas C., and Ashutosh Chilkoti. “Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins.” Nature Materials 15, no. 4 (April 2016): 419–24. https://doi.org/10.1038/nmat4521.

Nawroth, Jonas F., Jonathan R. McDaniel, Ashutosh Chilkoti, Rainer Jordan, and Robert Luxenhofer. “Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides.” Macromolecular Bioscience 16, no. 3 (March 2016): 322–33. https://doi.org/10.1002/mabi.201500376.

Mukerji, Ratul, Jeffrey Schaal, Xinghai Li, Jayanta Bhattacharyya, Daisuke Asai, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor.” Biomaterials 79 (February 2016): 79–87. https://doi.org/10.1016/j.biomaterials.2015.11.064.

Qi, Yizhi, Antonina Simakova, Nancy J. Ganson, Xinghai Li, Kelli M. Luginbuhl, Imran Özer, Wenge Liu, Michael S. Hershfield, Krzysztof Matyjaszewski, and Ashutosh Chilkoti. “A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity.” Nat Biomed Eng 1 (2016). https://doi.org/10.1038/s41551-016-0002.

Bhattacharyya, J., J. J. Bellucci, and A. Chilkoti. “Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering.” In Biomaterials from Nature for Advanced Devices and Therapies, 106–26, 2016. https://doi.org/10.1002/9781119126218.ch7.

Quiroz, Felipe García, and Ashutosh Chilkoti. “Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers.” Nature Materials 14, no. 11 (November 2015): 1164–71. https://doi.org/10.1038/nmat4418.

Li, Nan K., William H. Fuss, Lei Tang, Renpeng Gu, Ashutosh Chilkoti, Stefan Zauscher, and Yaroslava G. Yingling. “Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles.” Soft Matter 11, no. 42 (November 2015): 8236–45. https://doi.org/10.1039/c5sm01742d.

Bhattacharjee, Somnath, Wenge Liu, Wei-Han Wang, Isaac Weitzhandler, Xinghai Li, Yizhi Qi, Jinyao Liu, Yan Pang, Donald F. Hunt, and Ashutosh Chilkoti. “Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation.” Chembiochem : A European Journal of Chemical Biology 16, no. 17 (November 2015): 2451–55. https://doi.org/10.1002/cbic.201500439.

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa A. Van Heest, John S. Yi, Cody Baker, Zohreh Taherifard, David M. Margolis, et al. “Characterizing the Switching Thresholds of Magnetophoretic Transistors.” Adv Mater 27, no. 40 (October 28, 2015): 6176–80. https://doi.org/10.1002/adma.201502352.

Qi, Yizhi, and Ashutosh Chilkoti. “Protein-polymer conjugation-moving beyond PEGylation.” Current Opinion in Chemical Biology 28 (October 2015): 181–93. https://doi.org/10.1016/j.cbpa.2015.08.009.

Garanger, E., S. R. MacEwan, O. Sandre, A. Brûlet, L. Bataille, A. Chilkoti, and S. Lecommandoux. “Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core.” Macromolecules 48, no. 18 (September 22, 2015): 6617–27. https://doi.org/10.1021/acs.macromol.5b01371.

Roberts, Stefan, Michael Dzuricky, and Ashutosh Chilkoti. “Elastin-like polypeptides as models of intrinsically disordered proteins.” FEBS Letters 589, no. 19 Pt A (September 2015): 2477–86. https://doi.org/10.1016/j.febslet.2015.08.029.

Bhattacharyya, Jayanta, Joseph J. Bellucci, Isaac Weitzhandler, Jonathan R. McDaniel, Ivan Spasojevic, Xinghai Li, Chao-Chieh Lin, Jen-Tsan Ashley Chi, and Ashutosh Chilkoti. “A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models.” Nat Commun 6 (August 4, 2015): 7939. https://doi.org/10.1038/ncomms8939.

Han, Wei, Sarah R. MacEwan, Ashutosh Chilkoti, and Gabriel P. López. “Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles.” Nanoscale 7, no. 28 (July 2015): 12038–44. https://doi.org/10.1039/c5nr01407g.

Mastria, Eric M., Mingnan Chen, Jonathan R. McDaniel, Xinghai Li, Jinho Hyun, Mark W. Dewhirst, and Ashutosh Chilkoti. “Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma.” J Control Release 208 (June 28, 2015): 52–58. https://doi.org/10.1016/j.jconrel.2015.01.033.

Ghoorchian, A., J. R. Simon, B. Bharti, W. Han, X. Zhao, A. Chilkoti, and G. P. Lõpez. “Bioinspired reversibly cross-linked hydrogels comprising polypeptide micelles exhibit enhanced mechanical properties.” Advanced Functional Materials 25, no. 21 (June 1, 2015): 3122–30. https://doi.org/10.1002/adfm.201500699.

Kimmerling, K. A., B. D. Furman, D. S. Mangiapani, M. A. Moverman, S. M. Sinclair, J. L. Huebner, A. Chilkoti, et al. “Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.” Eur Cell Mater 29 (January 31, 2015): 124–39. https://doi.org/10.22203/ecm.v029a10.

Bellucci, Joseph J., Jayanta Bhattacharyya, and Ashutosh Chilkoti. “A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins.” Angewandte Chemie (International Ed. in English) 54, no. 2 (January 2015): 441–45. https://doi.org/10.1002/anie.201408126.

Hassouneh, Wafa, Ekaterina B. Zhulina, Ashutosh Chilkoti, and Michael Rubinstein. “Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles.” Macromolecules, 2015. https://doi.org/10.1021/acs.macromol.5b00431.

Liu, Jinyao, Wenge Liu, Isaac Weitzhandler, Jayanta Bhattacharyya, Xinghai Li, Jing Wang, Yizhi Qi, Somnath Bhattacharjee, and Ashutosh Chilkoti. “Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles.” Angewandte Chemie (International Ed. in English) 54, no. 3 (January 2015): 1002–6. https://doi.org/10.1002/anie.201409293.

McDaniel, Jonathan R., Isaac Weitzhandler, Sylvain Prevost, Kevin B. Vargo, Marie-Sousai Appavou, Daniel A. Hammer, Michael Gradzielski, and Ashutosh Chilkoti. “Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles.” Nano Letters 14, no. 11 (November 2014): 6590–98. https://doi.org/10.1021/nl503221p.

Li, Nan K., Felipe García Quiroz, Carol K. Hall, Ashutosh Chilkoti, and Yaroslava G. Yingling. “Molecular description of the LCST behavior of an elastin-like polypeptide.” Biomacromolecules 15, no. 10 (October 2014): 3522–30. https://doi.org/10.1021/bm500658w.

Hill, Ryan T., Klaudia M. Kozek, Angus Hucknall, David R. Smith, and Ashutosh Chilkoti. “Nanoparticle-Film Plasmon Ruler Interrogated with Transmission Visible Spectroscopy.” ACS Photonics 1, no. 10 (October 2014): 974–84. https://doi.org/10.1021/ph500190q.

Bhattacharyya, Jayanta, and Ashutosh Chilkoti. “Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors.” In Cancer Research, 74:4481–4481. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-4481.

Liu, Wenge, Ratul Mukerji, Xinghai Li, Jeff Schaal, Jayanta Bhattacharyya, Michael Zalutsky, and Ashutosh Chilkoti. “Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor.” In Cancer Research, 74:4583–4583. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-4583.

Yousefpour, Parisa, and Ashutosh Chilkoti. “Co-opting biology to deliver drugs.” Biotechnology and Bioengineering 111, no. 9 (September 2014): 1699–1716. https://doi.org/10.1002/bit.25307.

MacEwan, Sarah R., and Ashutosh Chilkoti. “Applications of elastin-like polypeptides in drug delivery.” Journal of Controlled Release : Official Journal of the Controlled Release Society 190 (September 2014): 314–30. https://doi.org/10.1016/j.jconrel.2014.06.028.

Chilkoti, Ashutosh. “Surface initiated polymerization and its applications in medicine.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 248. AMER CHEMICAL SOC, 2014.

Ghoorchian, Ali, Ashutosh Chilkoti, and Gabriel P. López. “Simple assay for proteases based on aggregation of stimulus-responsive polypeptides.” Analytical Chemistry 86, no. 12 (June 2014): 6103–10. https://doi.org/10.1021/ac5012574.

MacEwan, Sarah R., Wafa Hassouneh, and Ashutosh Chilkoti. “Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli.” Journal of Visualized Experiments : JoVE, no. 88 (June 2014). https://doi.org/10.3791/51583.

McDaniel, Jonathan R., Sarah R. MacEwan, Xinghai Li, D Christopher Radford, Chelsea D. Landon, Mark Dewhirst, and Ashutosh Chilkoti. “Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors.” Nano Lett 14, no. 5 (May 14, 2014): 2890–95. https://doi.org/10.1021/nl5009376.

Tang, Lei, Vinalia Tjong, Nan Li, Yaroslava G. Yingling, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles.” Advanced Materials (Deerfield Beach, Fla.) 26, no. 19 (May 2014): 3050–54. https://doi.org/10.1002/adma.201306049.

Chilkoti, Ashutosh. “Genetically encoded polypeptide nanoparticles for delivery of drugs.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 247. AMER CHEMICAL SOC, 2014.

Tjong, Vinalia, Lei Tang, Stefan Zauscher, and Ashutosh Chilkoti. “"Smart" DNA interfaces.” Chemical Society Reviews 43, no. 5 (March 2014): 1612–26. https://doi.org/10.1039/c3cs60331h.

Mastria, E., and A. Chilkoti. “Genetically encoded smart peptide polymers for biomedicine.” MRS Bulletin 39, no. 1 (January 27, 2014): 35–43. https://doi.org/10.1557/mrs.2013.313.

Qi, Y., and A. Chilkoti. “Growing polymers from peptides and proteins: A biomedical perspective.” Polymer Chemistry 5, no. 2 (January 21, 2014): 266–76. https://doi.org/10.1039/c3py01089a.

MacEwan, S. R., W. Hassouneh, and A. Chilkoti. “Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli.” Journal of Visualized Experiments : JoVE, no. 88 (January 1, 2014).

MacEwan, Sarah R., and Ashutosh Chilkoti. “Controlled apoptosis by a thermally toggled nanoscale amplifier of cellular uptake.” Nano Letters 14, no. 4 (January 2014): 2058–64. https://doi.org/10.1021/nl5002313.

Quiroz, F. G., and A. Chilkoti. “The language of protein polymers.” In ACS Symposium Series, 1170:15–33, 2014. https://doi.org/10.1021/bk-2014-1170.ch002.

Li, L., O. Im, C. Ashutosh, and G. P. López. “Encapsulation of stimuli-responsive fusion proteins in silica: Thermally responsive metal ion-sensitive hybrid membranes.” Materials Research Society Symposium Proceedings 1498 (December 1, 2013): 169–75. https://doi.org/10.1557/opl.2013.332.

Qi, Y., M. Amiram, W. Gao, and A. Chilkoti. “Sortase-mediated initiator attachment for in situ grafting of a PEG-based polymer brush from the C terminus of green fluorescent protein.” J Control Release 172, no. 1 (November 28, 2013): e121. https://doi.org/10.1016/j.jconrel.2013.08.288.

Amiram, M., K. M. Luginbuhl, X. Li, M. N. Feinglos, and A. Chilkoti. “A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection.” Journal of Controlled Release : Official Journal of the Controlled Release Society 172, no. 1 (November 2013): 144–51. https://doi.org/10.1016/j.jconrel.2013.07.021.

Sinclair, S Michael, Jayanta Bhattacharyya, Jonathan R. McDaniel, David M. Gooden, Ramesh Gopalaswamy, Ashutosh Chilkoti, and Lori A. Setton. “A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation.” Journal of Controlled Release : Official Journal of the Controlled Release Society 171, no. 1 (October 2013): 38–47. https://doi.org/10.1016/j.jconrel.2013.06.032.

Chilkoti, Ashutosh. “Syntax of "smart" peptide polymers governs their function.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 246. AMER CHEMICAL SOC, 2013.

Garanger, Elisabeth, Sarah Mac Ewan, Annie Brulet, Laure Bataille, Olivier Sandre, Ashutosh Chilkoti, and Sebastien Lecommandoux. “Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 246. AMER CHEMICAL SOC, 2013.

Tang, Lei, Vinalia Tjong, Renpeng Gu, Ashutosh Chilkoti, and Stefan Zauscher. “Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 246. AMER CHEMICAL SOC, 2013.

Chilkoti, Ashutosh. “Genetically engineered polypeptide conjugates and fusions for drug delivery.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 246. AMER CHEMICAL SOC, 2013.

McDaniel, Jonathan R., Mark W. Dewhirst, and Ashutosh Chilkoti. “Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia.” Int J Hyperthermia 29, no. 6 (September 2013): 501–10. https://doi.org/10.3109/02656736.2013.819999.

Tjong, V., H. Yu, A. Hucknall, and A. Chilkoti. “Amplified fluorescence detection of DNA and RNA hybridization by surface initiated enzymatic polymerization (SIEP).” Technical Proceedings of the 2013 Nsti Nanotechnology Conference and Expo Nsti Nanotech 2013 3 (August 9, 2013): 32–36.

Khan, M Nuruzzaman, Vinalia Tjong, Ashutosh Chilkoti, and Michael Zharnikov. “Spectroscopic study of a DNA brush synthesized in situ by surface initiated enzymatic polymerization.” The Journal of Physical Chemistry. B 117, no. 34 (August 2013): 9929–38. https://doi.org/10.1021/jp404774x.

McDaniel, Jonathan R., D Christopher Radford, and Ashutosh Chilkoti. “A unified model for de novo design of elastin-like polypeptides with tunable inverse transition temperatures.” Biomacromolecules 14, no. 8 (August 2013): 2866–72. https://doi.org/10.1021/bm4007166.

Qi, Yizhi, Miriam Amiram, Weiping Gao, Dewey G. McCafferty, and Ashutosh Chilkoti. “Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein.” Macromolecular Rapid Communications 34, no. 15 (August 2013): 1256–60. https://doi.org/10.1002/marc.201300460.

Hassouneh, Wafa, Michelle L. Nunalee, M Coleman Shelton, and Ashutosh Chilkoti. “Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides.” Biomacromolecules 14, no. 7 (July 2013): 2347–53. https://doi.org/10.1021/bm400464s.

Weinberger, A., S. Macewan, T. Schmatko, A. Schroder, A. Chilkoti, and C. M. Marques. “Interactions of elastin-like polypeptides with model membranes on GUVs.” In EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 42:S158–S158. SPRINGER, 2013.

Kurzbach, Dennis, Wafa Hassouneh, Jonathan R. McDaniel, Eva A. Jaumann, Ashutosh Chilkoti, and Dariush Hinderberger. “Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers.” Journal of the American Chemical Society 135, no. 30 (July 2013): 11299–308. https://doi.org/10.1021/ja4047872.

Weller, D., J. R. McDaniel, K. Fischer, A. Chilkoti, and M. Schmidt. “Cylindrical polymer brushes with elastin-like polypeptide side chains.” Macromolecules 46, no. 12 (June 25, 2013): 4966–71. https://doi.org/10.1021/ma400917t.

Christensen, Trine, Wafa Hassouneh, Kimberley Trabbic-Carlson, and Ashutosh Chilkoti. “Predicting transition temperatures of elastin-like polypeptide fusion proteins.” Biomacromolecules 14, no. 5 (May 2013): 1514–19. https://doi.org/10.1021/bm400167h.

Bhattacharyya, Jayanta, Jonathan McDaniel, and Ashutosh Chilkoti. “Abstract 4509: Genetically encoded chimeric polypeptide nanoparticles for paclitaxel delivery to triple negative breast cancer.” In Cancer Research, 73:4509–4509. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/1538-7445.am2013-4509.

Liu, Wenge, Jonathan R. McDaniel, Xinghai Li, Jeffery Schaal, Jayanta Bhattacharyya, Michael R. Zalutsky, and Ashutosh Chilkoti. “Abstract 4341: A novel injectable polymer liquid that self-assembles into radioactive “seeds” for brachytherapy.” In Cancer Research, 73:4341–4341. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/1538-7445.am2013-4341.

Schaal, Jeffrey L., Wenge Liu, Xinghai Li, Michael Zalutsky, and Ashutosh Chilkoti. “Abstract 5615: Evaluation of the antitumoral efficacy and toxicity of injectable, polymeric radionuclide seeds in a noninvasive preclinical prostate tumor model.” In Cancer Research, 73:5615–5615. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/1538-7445.am2013-5615.

Caudill, Cassie, Jayanta Bhattacharyya, and Ashutosh Chilkoti. “Delivery of paclitaxel with elastin-like polypeptides.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 245. AMER CHEMICAL SOC, 2013.

Sinclair, S. M., J. Bhattacharyya, D. Little, R. D. Bowles, D. M. Gooden, E. J. Toone, A. Chilkoti, and L. A. Setton. “Pharmacokinetics of a thermally responsive curcumin conjugate for local antagonism of neuroinflammation in disc herniation.” In Osteoarthritis and Cartilage, 21:S292–93. Elsevier BV, 2013. https://doi.org/10.1016/j.joca.2013.02.613.

Bellucci, Joseph J., Miriam Amiram, Jayanta Bhattacharyya, Dewey McCafferty, and Ashutosh Chilkoti. “Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides.” Angewandte Chemie (International Ed. in English) 52, no. 13 (March 2013): 3703–8. https://doi.org/10.1002/anie.201208292.

McDaniel, Jonathan R., Jayanta Bhattacharyya, Kevin B. Vargo, Wafa Hassouneh, Daniel A. Hammer, and Ashutosh Chilkoti. “Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.” Angewandte Chemie (International Ed. in English) 52, no. 6 (February 2013): 1683–87. https://doi.org/10.1002/anie.201200899.

Amiram, Miriam, Kelli M. Luginbuhl, Xinghai Li, Mark N. Feinglos, and Ashutosh Chilkoti. “Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control.” Proceedings of the National Academy of Sciences of the United States of America 110, no. 8 (February 2013): 2792–97. https://doi.org/10.1073/pnas.1214518110.

Tjong, Vinalia, Hua Yu, Angus Hucknall, and Ashutosh Chilkoti. “Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization.” Analytical Chemistry 85, no. 1 (January 2013): 426–33. https://doi.org/10.1021/ac303132j.

Hill, R. T., and A. Chilkoti. “Surface Patterning.” In Biomaterials Science an Introduction to Materials Third Edition, 276–301, 2013. https://doi.org/10.1016/B978-0-08-087780-8.00028-0.

Lassiter, J Britt, Felicia McGuire, Jack J. Mock, Cristian Ciracì, Ryan T. Hill, Benjamin J. Wiley, Ashutosh Chilkoti, and David R. Smith. “Plasmonic waveguide modes of film-coupled metallic nanocubes.” Nano Letters 13, no. 12 (January 2013): 5866–72. https://doi.org/10.1021/nl402660s.

MacEwan, Sarah R., and Ashutosh Chilkoti. “Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents.” Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology 5, no. 1 (January 2013): 31–48. https://doi.org/10.1002/wnan.1197.

Thapa, Arjun, Wei Han, Robin H. Simons, Ashutosh Chilkoti, Eva Y. Chi, and Gabriel P. López. “Effect of detergents on the thermal behavior of elastin-like polypeptides.” Biopolymers 99, no. 1 (January 2013): 55–62. https://doi.org/10.1002/bip.22137.

Moreau, Antoine, Cristian Ciracì, Jack J. Mock, Ryan T. Hill, Qiang Wang, Benjamin J. Wiley, Ashutosh Chilkoti, and David R. Smith. “Controlled-reflectance surfaces with film-coupled colloidal nanoantennas.” Nature 492, no. 7427 (December 2012): 86–89. https://doi.org/10.1038/nature11615.

Liu, Wenge, Jonathan McDaniel, Xinghai Li, Daisuke Asai, Felipe Garcia Quiroz, Jeffery Schaal, Ji Sun Park, Michael Zalutsky, and Ashutosh Chilkoti. “Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ.” Cancer Res 72, no. 22 (November 15, 2012): 5956–65. https://doi.org/10.1158/0008-5472.CAN-12-2127.

Manzoor, Ashley A., Lars H. Lindner, Chelsea D. Landon, Ji-Young Park, Andrew J. Simnick, Matthew R. Dreher, Shiva Das, et al. “Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors.” Cancer Res 72, no. 21 (November 1, 2012): 5566–75. https://doi.org/10.1158/0008-5472.CAN-12-1683.

Khan, M Nuruzzaman, Vinalia Tjong, Ashutosh Chilkoti, and Michael Zharnikov. “Fabrication of ssDNA/oligo(ethylene glycol) monolayers and complex nanostructures by an irradiation-promoted exchange reaction.” Angewandte Chemie (International Ed. in English) 51, no. 41 (October 2012): 10303–6. https://doi.org/10.1002/anie.201204245.

Hill, Ryan T., Jack J. Mock, Angus Hucknall, Scott D. Wolter, Nan M. Jokerst, David R. Smith, and Ashutosh Chilkoti. “Plasmon ruler with angstrom length resolution.” ACS Nano 6, no. 10 (October 2012): 9237–46. https://doi.org/10.1021/nn3035809.

Kwok, Kevin W. H., Melanie Auffan, Appala R. Badireddy, Clay M. Nelson, Mark R. Wiesner, Ashutosh Chilkoti, Jie Liu, Stella M. Marinakos, and David E. Hinton. “Uptake of silver nanoparticles and toxicity to early life stages of Japanese medaka (Oryzias latipes): effect of coating materials.” Aquatic Toxicology (Amsterdam, Netherlands) 120–121 (September 2012): 59–66. https://doi.org/10.1016/j.aquatox.2012.04.012.

Chilkoti, Ashutosh. “Biomolecular toolbox for the in situ synthesis of protein-polymer conjugates.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 244. AMER CHEMICAL SOC, 2012.

Xu, Donghua, Daisuke Asai, Ashutosh Chilkoti, and Stephen L. Craig. “Rheological properties of cysteine-containing elastin-like polypeptide solutions and hydrogels.” Biomacromolecules 13, no. 8 (August 2012): 2315–21. https://doi.org/10.1021/bm300760s.

Ciracì, C., R. T. Hill, J. J. Mock, Y. Urzhumov, A. I. Fernández-Domínguez, S. A. Maier, J. B. Pendry, A. Chilkoti, and D. R. Smith. “Probing the ultimate limits of plasmonic enhancement.” Science (New York, N.Y.) 337, no. 6098 (August 2012): 1072–74. https://doi.org/10.1126/science.1224823.

Asai, Daisuke, Donghua Xu, Wenge Liu, Felipe Garcia Quiroz, Daniel J. Callahan, Michael R. Zalutsky, Stephen L. Craig, and Ashutosh Chilkoti. “Protein polymer hydrogels by in situ, rapid and reversible self-gelation.” Biomaterials 33, no. 21 (July 2012): 5451–58. https://doi.org/10.1016/j.biomaterials.2012.03.083.

Hubbell, Jeffrey A., and Ashutosh Chilkoti. “Chemistry. Nanomaterials for drug delivery.” Science (New York, N.Y.) 337, no. 6092 (July 2012): 303–5. https://doi.org/10.1126/science.1219657.

Macewan, Sarah R., and Ashutosh Chilkoti. “Digital switching of local arginine density in a genetically encoded self-assembled polypeptide nanoparticle controls cellular uptake.” Nano Letters 12, no. 6 (June 2012): 3322–28. https://doi.org/10.1021/nl301529p.

McDaniel, Jonathan R., Sarah R. Macewan, Mark Dewhirst, and Ashutosh Chilkoti. “Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia.” J Control Release 159, no. 3 (May 10, 2012): 362–67. https://doi.org/10.1016/j.jconrel.2012.02.030.

Hassouneh, Wafa, Karl Fischer, Sarah R. MacEwan, Robert Branscheid, Chuan Lawrence Fu, Rihe Liu, Manfred Schmidt, and Ashutosh Chilkoti. “Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.” Biomacromolecules 13, no. 5 (May 2012): 1598–1605. https://doi.org/10.1021/bm300321n.

Callahan, Daniel J., Wenge Liu, Xinghai Li, Matthew R. Dreher, Wafa Hassouneh, Minkyu Kim, Piotr Marszalek, and Ashutosh Chilkoti. “Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution.” Nano Letters 12, no. 4 (April 2012): 2165–70. https://doi.org/10.1021/nl300630c.

Mock, Jack J., Ryan T. Hill, Yu-Ju Tsai, Ashutosh Chilkoti, and David R. Smith. “Probing dynamically tunable localized surface plasmon resonances of film-coupled nanoparticles by evanescent wave excitation.” Nano Letters 12, no. 4 (April 2012): 1757–64. https://doi.org/10.1021/nl204596h.

Ferris, Robert, Angus Hucknall, Byung Seok Kwon, Ashutosh Chilkoti, and Stefan Zauscher. “Field-induced nanolithography for the patterning of non-fouling polymer brushes.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 243, 2012.

Chilkoti, Ashutosh. “Genetically encoded stimulus responsive elastin-like polypeptides: Applications in drug delivery.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 243. AMER CHEMICAL SOC, 2012.

Fluegel, Sabine, Tina Kiefer, Nils Heimann, Jasmin Buehler, Karl Fischer, Jonathan McDaniel, Ashutosh Chilkoti, and Manfred Schmidt. “Conjugates of polypeptides and synthetic polymers with oligonucleotides: Stars, micelles and multiblockcopolymers.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 243. AMER CHEMICAL SOC, 2012.

Tjong, V., J. Zhang, A. Chilkoti, and S. Zauscher. “Stimulus-Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications,” February 3, 2012, 1–30. https://doi.org/10.1002/9781118181249.ch1.

Christensen, T., W. Hassouneh, D. J. Callahan, and A. Chilkoti. “Protein switches” 3 (January 1, 2012): 238–66. https://doi.org/10.1016/B978-0-12-374920-8.00316-7.

Nusz, G., and A. Chilkoti. “Individual plasmonic nanostructures as label free biosensors.” In Nanoplasmonic Sensors, 105–26, 2012. https://doi.org/10.1007/978-1-4614-3933-2_5.

Hassouneh, Wafa, Sarah R. MacEwan, and Ashutosh Chilkoti. “Fusions of elastin-like polypeptides to pharmaceutical proteins.” Methods in Enzymology 502 (January 2012): 215–37. https://doi.org/10.1016/b978-0-12-416039-2.00024-0.

Chen, S. Y., J. J. Mock, R. T. Hill, A. Chilkoti, D. R. Smith, and A. A. Lazarides. “Raman antenna formed by molecule/plasmonic nanostructure hybrid system.” Optics Infobase Conference Papers, December 1, 2011.

Seekell, Kevin, Matthew J. Crow, Stella Marinakos, Julie Ostrander, Ashutosh Chilkoti, and Adam Wax. “Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles.” Journal of Biomedical Optics 16, no. 11 (November 2011): 116003. https://doi.org/10.1117/1.3646529.

Ferris, Robert, Angus Hucknall, Byung Seok Kwon, Tao Chen, Ashutosh Chilkoti, and Stefan Zauscher. “Field-induced nanolithography for patterning of non-fouling polymer brush surfaces.” Small (Weinheim an Der Bergstrasse, Germany) 7, no. 21 (November 2011): 3032–37. https://doi.org/10.1002/smll.201100923.

Simnick, Andrew J., Miriam Amiram, Wenge Liu, Gabi Hanna, Mark W. Dewhirst, Christopher D. Kontos, and Ashutosh Chilkoti. “In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide.” J Control Release 155, no. 2 (October 30, 2011): 144–51. https://doi.org/10.1016/j.jconrel.2011.06.044.

Chen, S. Y., J. J. Mock, R. T. Hill, A. Chilkoti, D. R. Smith, and A. A. Lazarides. “Raman antenna formed by molecule/plasmonic nanostructure hybrid system.” 2011 Conference on Lasers and Electro Optics Laser Science to Photonic Applications CLEO 2011, September 1, 2011.

Nusz, Gregory J., Stella M. Marinakos, Srinath Rangarajan, and Ashutosh Chilkoti. “Dual-order snapshot spectral imaging of plasmonic nanoparticles.” Applied Optics 50, no. 21 (July 2011): 4198–4206. https://doi.org/10.1364/ao.50.004198.

Gao, W., D. Xu, D. W. Lim, S. L. Craig, and A. Chilkoti. “In situ growth of a thermoresponsive polymer from a genetically engineered elastin-like polypeptide.” Polymer Chemistry 2, no. 7 (July 1, 2011): 1561–66. https://doi.org/10.1039/c1py00074h.

Tjong, Vinalia, Hua Yu, Angus Hucknall, Srinath Rangarajan, and Ashutosh Chilkoti. “Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization.” Analytical Chemistry 83, no. 13 (July 2011): 5153–59. https://doi.org/10.1021/ac200946t.

Fluegel, Sabine, Jasmin Buehler, Karl Fischer, Jonathan R. McDaniel, Ashutosh Chilkoti, and Manfred Schmidt. “Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles.” Chemistry (Weinheim an Der Bergstrasse, Germany) 17, no. 20 (May 2011): 5503–6. https://doi.org/10.1002/chem.201100436.

Crow, M. J., K. Seekell, S. Marinakos, J. Ostrander, A. Chilkoti, and A. P. Wax. “Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles.” Progress in Biomedical Optics and Imaging Proceedings of SPIE 7911 (April 29, 2011). https://doi.org/10.1117/12.874093.

Ahmad, Shah Alang, Graham J. Leggett, Angus Hucknall, and Ashutosh Chilkoti. “Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization.” Biointerphases 6, no. 1 (March 2011): 8–15. https://doi.org/10.1116/1.3553579.

Yang, Peng, Stella M. Marinakos, and Ashutosh Chilkoti. “Spatially addressable chemoselective C-terminal ligation of an intein fusion protein from a complex mixture to a hydrazine-terminated surface.” Langmuir : The ACS Journal of Surfaces and Colloids 27, no. 4 (February 2011): 1463–71. https://doi.org/10.1021/la104186n.

Amiram, Miriam, Felipe Garcia Quiroz, Daniel J. Callahan, and Ashutosh Chilkoti. “A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers.” Nat Mater 10, no. 2 (February 2011): 141–48. https://doi.org/10.1038/nmat2942.

Williams, Corin, Xin Q. Brown, Erzsebet Bartolak-Suki, Hongwei Ma, Ashutosh Chilkoti, and Joyce Y. Wong. “The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells.” Biomaterials 32, no. 2 (January 2011): 410–18. https://doi.org/10.1016/j.biomaterials.2010.08.105.

Crow, Matthew J., Stella M. Marinakos, J Michael Cook, Ashutosh Chilkoti, and Adam Wax. “Plasmonic flow cytometry by immunolabeled nanorods.” Cytometry A 79, no. 1 (January 2011): 57–65. https://doi.org/10.1002/cyto.a.20994.

Chen, Mingnan, Jonathan R. McDaniel, J Andrew Mackay, and Ashutosh Chilkoti. “NANOSCALE SELF-ASSEMBLY FOR DELIVERY OF THERAPEUTICS AND IMAGING AGENTS.” Technology and Innovation 13, no. 1 (January 2011): 5–25. https://doi.org/10.3727/194982411x13003853539948.

McDaniel, Jonathan R., Daniel J. Callahan, and Ashutosh Chilkoti. “Drug delivery to solid tumors by elastin-like polypeptides.” Advanced Drug Delivery Reviews 62, no. 15 (December 2010): 1456–67. https://doi.org/10.1016/j.addr.2010.05.004.

Nettles, Dana L., Ashutosh Chilkoti, and Lori A. Setton. “Applications of elastin-like polypeptides in tissue engineering.” Advanced Drug Delivery Reviews 62, no. 15 (December 2010): 1479–85. https://doi.org/10.1016/j.addr.2010.04.002.

Mackay, J Andrew, Daniel J. Callahan, Kelly N. Fitzgerald, and Ashutosh Chilkoti. “Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides.” Biomacromolecules 11, no. 11 (November 2010): 2873–79. https://doi.org/10.1021/bm100571j.

Fluegel, Sabine, Karl Fischer, Jonathan R. McDaniel, Ashutosh Chilkoti, and Manfred Schmidt. “Chain stiffness of elastin-like polypeptides.” Biomacromolecules 11, no. 11 (November 2010): 3216–18. https://doi.org/10.1021/bm100965y.

Chen, Shiuan-Yeh, Jack J. Mock, Ryan T. Hill, Ashutosh Chilkoti, David R. Smith, and Anne A. Lazarides. “Gold nanoparticles on polarizable surfaces as Raman scattering antennas.” ACS Nano 4, no. 11 (November 2010): 6535–46. https://doi.org/10.1021/nn101644s.

Hill, Ryan T., Jack J. Mock, Yaroslav Urzhumov, David S. Sebba, Steven J. Oldenburg, Shiuan-Yeh Chen, Anne A. Lazarides, Ashutosh Chilkoti, and David R. Smith. “Leveraging nanoscale plasmonic modes to achieve reproducible enhancement of light.” Nano Letters 10, no. 10 (October 2010): 4150–54. https://doi.org/10.1021/nl102443p.

Gao, Weiping, Wenge Liu, Trine Christensen, Michael R. Zalutsky, and Ashutosh Chilkoti. “In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.” Proc Natl Acad Sci U S A 107, no. 38 (September 21, 2010): 16432–37. https://doi.org/10.1073/pnas.1006044107.

Hassouneh, Wafa, Trine Christensen, and Ashutosh Chilkoti. “Elastin-like polypeptides as a purification tag for recombinant proteins.” Current Protocols in Protein Science Chapter 6 (August 2010): 6.11.1-6.11.16. https://doi.org/10.1002/0471140864.ps0611s61.

MacEwan, Sarah R., Daniel J. Callahan, and Ashutosh Chilkoti. “Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery.” Nanomedicine (London, England) 5, no. 5 (July 2010): 793–806. https://doi.org/10.2217/nnm.10.50.

Alang Ahmad, Shahrul, Angus Hucknall, Ashutosh Chilkoti, and Graham J. Leggett. “Protein patterning by UV-induced photodegradation of poly(oligo(ethylene glycol) methacrylate) brushes.” Langmuir : The ACS Journal of Surfaces and Colloids 26, no. 12 (June 2010): 9937–42. https://doi.org/10.1021/la100438d.

Liu, Wenge, J Andrew MacKay, Matthew R. Dreher, Mingnan Chen, Jonathan R. McDaniel, Andrew J. Simnick, Daniel J. Callahan, Michael R. Zalutsky, and Ashutosh Chilkoti. “Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model.” J Control Release 144, no. 1 (May 21, 2010): 2–9. https://doi.org/10.1016/j.jconrel.2010.01.032.

Jenness, Nathan J., Ryan T. Hill, Angus Hucknall, Ashutosh Chilkoti, and Robert L. Clark. “A versatile diffractive maskless lithography for single-shot and serial microfabrication.” Optics Express 18, no. 11 (May 2010): 11754–62. https://doi.org/10.1364/oe.18.011754.

McDaniel, Jonathan R., J Andrew Mackay, Felipe García Quiroz, and Ashutosh Chilkoti. “Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.” Biomacromolecules 11, no. 4 (April 2010): 944–52. https://doi.org/10.1021/bm901387t.

Simnick, Andrew J., C Alexander Valencia, Rihe Liu, and Ashutosh Chilkoti. “Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.” ACS Nano 4, no. 4 (April 2010): 2217–27. https://doi.org/10.1021/nn901732h.

Meyer, J. N., C. A. Lord, X. Y. Yang, E. A. Turner, A. R. Badireddy, S. Marinakos, A. Chilkoti, M. R. Wiesner, and M. Auffan. “Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans.” Aquatic Toxicol 100 (2010): 140–50.

Nettles, Dana L., Mansoor A. Haider, Ashutosh Chilkoti, and Lori A. Setton. “Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds.” Tissue Engineering. Part A 16, no. 1 (January 2010): 11–20. https://doi.org/10.1089/ten.tea.2009.0134.

MacEwan, Sarah R., and Ashutosh Chilkoti. “Elastin-like polypeptides: biomedical applications of tunable biopolymers.” Biopolymers 94, no. 1 (January 2010): 60–77. https://doi.org/10.1002/bip.21327.

MacKay, J Andrew, Mingnan Chen, Jonathan R. McDaniel, Wenge Liu, Andrew J. Simnick, and Ashutosh Chilkoti. “Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection.” NATURE MATERIALS 8, no. 12 (December 2009): 993–99. https://doi.org/10.1038/NMAT2569.

Cho, Younhee, Laura B. Sagle, Satoshi Iimura, Yanjie Zhang, Jaibir Kherb, Ashutosh Chilkoti, J Martin Scholtz, and Paul S. Cremer. “Hydrogen bonding of beta-turn structure is stabilized in D(2)O.” Journal of the American Chemical Society 131, no. 42 (October 2009): 15188–93. https://doi.org/10.1021/ja9040785.

Gao, Weiping, Wenge Liu, J Andrew Mackay, Michael R. Zalutsky, Eric J. Toone, and Ashutosh Chilkoti. “In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics.” Proc Natl Acad Sci U S A 106, no. 36 (September 8, 2009): 15231–36. https://doi.org/10.1073/pnas.0904378106.

Nettles, Dana L., Ashutosh Chilkoti, and Lori A. Setton. “Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds.” Tissue Engineering. Part A 15, no. 8 (August 2009): 2113–21. https://doi.org/10.1089/ten.tea.2008.0448.

Christensen, Trine, Miriam Amiram, Sue Dagher, Kimberly Trabbic-Carlson, Mohammed F. Shamji, Lori A. Setton, and Ashutosh Chilkoti. “Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins.” Protein Science : A Publication of the Protein Society 18, no. 7 (July 2009): 1377–87. https://doi.org/10.1002/pro.157.

Hucknall, A., S. Rangarajan, and A. Chilkoti. “In pursuit of zero: Polymer brushes that resist the adsorption of proteins.” Advanced Materials 21, no. 23 (June 19, 2009): 2441–46. https://doi.org/10.1002/adma.200900383.

Crow, M., S. Marinakos, A. Chilkoti, and A. Wax. “Simultaneous molecular imaging of EGFR and HER2 using hyperspectral darkfield microscopy and immunotargeted nanoparticles.” Progress in Biomedical Optics and Imaging Proceedings of SPIE 7192 (June 12, 2009). https://doi.org/10.1117/12.808968.

Hucknall, Angus, Andrew J. Simnick, Ryan T. Hill, Ashutosh Chilkoti, Andres Garcia, Matthew S. Johannes, Robert L. Clark, Stefan Zauscher, and Buddy D. Ratner. “Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale.” Biointerphases 4, no. 2 (June 2009): FA50–57. https://doi.org/10.1116/1.3151968.

Zauscher, Stefan, and Ashutosh Chilkoti. “Biological applications of polymer brushes. Preface.” Biointerphases 4, no. 2 (June 2009): FA1–2. https://doi.org/10.1116/1.3149787.

Hucknall, Angus, Dong-Hwan Kim, Srinath Rangarajan, Ryan T. Hill, William M. Reichert, and Ashutosh Chilkoti. “Simple Fabrication of Antibody Microarrays on Nonfouling Polymer Brushes with Femtomolar Sensitivity for Protein Analytes in Serum and Blood.” Advanced Materials (Deerfield Beach, Fla.) 21, no. 19 (May 2009): 1968–71. https://doi.org/10.1002/adma.200803125.